911364-08-4Relevant articles and documents
In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis
Deb, Pran Kishore,Al-Shar’i, Nizar A.,Venugopala, Katharigatta N.,Pillay, Melendhran,Borah, Pobitra
, p. 869 - 884 (2021)
The alarming increase in multi- and extensively drug-resistant (MDR and XDR) strains of Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for novel, effective, and safer therapeutics. To this end, a series of 3,5-disubstitu
Design, microwave assisted synthesis and characterization of substituted 1,2,4-oxadiazole analogues as promising pharmacological agents
Venugopala, Katharigatta N.
, p. 1767 - 1770 (2017/06/27)
Microwave assisted synthesis of a series of 3,5-disubstituted-1,2,4-oxadiazole analogues (3a-j) has been achieved between 5-(chloromethyl)-3-substituted phenyl-1,2,4-oxadiazoles (2a-j) and substituted benzophenone in presence of potassium carbonate in ace
Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl} -(phenyl)-methanones
Rai, Neithnadka Premsai,Narayanaswamy, Venugopala Katharigatta,Govender, Thavendran,Manuprasad,Shashikanth, Sheena,Arunachalam, Pirama Nayagam
experimental part, p. 2677 - 2682 (2010/07/09)
In the present investigation, a series of novel {5-chloro-2-[(3-(substitutedphenyl)-1,2,4-oxadiazol-5-yl)-methoxy]-pheny l}-(phenyl)-methanones (3a-i) have been synthesized from 5-(chloromethyl)-3-substitutedphenyl-1,2,4-oxadiazole (2a-i). The newly synth
INHIBITORS OF HISTONE DEACETYLASE
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Page/Page column 242; 243, (2010/11/24)
This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I); wherein Y, L, Z, W, X, Q, R1, R2 and R3 are as defined in the specification.