911428-63-2Relevant articles and documents
A four-component synthesis of highly substituted imidazole derivatives
Gwiazda, Maciej,Reissig, Hans-Ulrich
, p. 1683 - 1686 (2006)
Addition of lithiated methoxyallene 1 to imines 2 provided allenyl amines 3, which upon reaction with iodine and nitriles furnished dihydroimidazole derivatives 5. Treatment of these intermediates with strong acids such as trifluoromethane sulfonic acid a
Highly substituted imidazole derivatives from a new four-component synthesis employing methoxyallene
Gwiazda, Maciej,Reissig, Hans-Ulrich
, p. 990 - 994 (2008/09/21)
A novel four-component reaction of alkoxyallenes with imines, iodine, and nitriles provided highly substituted imidazole derivatives in high overall yields. The simple three step protocol, exemplified by the reaction of methoxyallene (1) with imine 2, ace