911430-71-2Relevant academic research and scientific papers
5′-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase
Casanova, Elena,Hernández, Ana-Isabel,Priego, Eva-María,Liekens, Sandra,Camarasa, María-José,Balzarini, Jan,Pérez-Pérez, María-Jesús
, p. 5562 - 5570 (2006)
On the basis of our previous findings that 5′-O-tritylinosine (KIN59) behaves as an allosteric inhibitor of the angiogenic enzyme thymidine phosphorylase (TPase), we have undertaken the synthesis and enzymatic evaluation of a novel series of nucleoside an
