911663-34-8

Upstream product

• 3417-91-2 L-tyrosine methyl ester HCl 
• 1080-06-4 L-Tyr-OMe 
• 24424-99-5 di-tert-butyl dicarbonate 
• 911663-30-4 N,N-bis(tert-butoxycarbonyl)-O-(tert-butoxycarbonyl)-L-tyrosine methyl ester 

Downstream Products

• 312328-59-9 N-Alloc-(S,R)Bht-OH 
• 1417985-79-5 C₄₅H₅₃N₇O₁₄ 
• 1426958-03-3 C₅₁H₅₇N₇O₁₃S 
• 1417985-88-6 C₁₄H₁₇NO₆ 

Relevant academic research and scientific papers

Total Synthesis of the Putative Structure of Asperipin-2a and Stereochemical Reassignment

The total synthesis of the putative structure of asperipin-2a is described. The synthesis features ether cross-links between the phenolic oxygen of Tyr6 and the β position of Tyr3 and the phenolic oxygen of Tyr3 and the β position of Hpp1 in the unique 17- and 14-membered bicyclic structure of asperipin-2a, respectively. The synthesized putative structure does not match the natural product, and a stereochemical reassignment is postulated.

Expedient synthesis of threo-β-hydroxy-α-amino acid derivatives: Phenylalanine, tyrosine, histidine, and tryptophan

An expedient synthesis of enantiomerically pure threo-β-hydroxy- α-amino acid derivatives of phenylalanine, tyrosine, histidine, and tryptophan is described. The NBS-mediated radical bromination of the N,N-di-tert-butoxycarbonyl protected α-amino acids an