911840-80-7

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 911841-20-8 C₄₁H₆₆N₁₀O₈ 
• 1402920-39-1 2-mexylamino-4-methylamino-6-(4-aminophenylamino)-1,3,5-triazine 
• 1402920-40-4 2-mexylamino-4-methylamino-6-(4-azidophenylamino)-1,3,5-triazine 
• 1402920-41-5 C₁₉H₁₉N₇ 
• 1402920-42-6 C₁₉H₂₁N₇O 
• 1402920-43-7 2-methylamino-4-mexylamino-6-[(3-formylphenyl)-amino]-1,3,5-triazine 
• 1402920-44-8 2-mexylamino-4-methylamino-6-(3-carboxyphenylamino)-1,3,5-triazine 
• 1402920-45-9 C₂₀H₂₂N₆O₂ 
• 1402920-46-0 C₁₈H₁₉N₇O₂ 
• 1402920-47-1 C₁₈H₂₆N₆ 
• 1402920-54-0 C₃₆H₃₈N₁₂S₂ 
• 1402920-07-3 C₁₈H₂₀N₆ 
• 1402920-08-4 C₁₉H₂₂N₆ 
• 1402920-09-5 C₁₉H₂₂N₆ 

Relevant academic research and scientific papers

One ring to rule them all: Effect of aryl substitution on glass-forming ability in mexylaminotriazine molecular glasses

Mexylaminotriazines are an exciting new class of small molecules capable of forming glassy phases (molecular glasses) that have shown outstanding glass-forming properties and resistance to crystallization. The effect of the structure of the 'headgroup' at the 2-position of the triazine ring on glass-forming properties has been studied, but the role of the arylamino substituents is unclear, though it has been shown that one of the aryl groups can be substituted with other aryl groups without loss of glass-forming ability. Herein, a library of mexylaminotriazine derivatives with various arylamino and cycloalkylamino groups has been synthesized and characterized. It was found that glass-forming ability is tolerant to a wide range of substituents, with all the compounds reported being capable of forming glassy phases, and only one compound crystallizing upon heating. On the other hand, the structure of the ancillary group has a profound impact on the glass transition temperatures (Tg) of the compounds, with values ranging from 52 to 131 °C having been obtained. Several trends between substitution pattern and T g were observed.

Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-Diamino-piperidinyl triazines

Structure-activity relationships of the 3,5-diamino-piperidinyl triazine series, a novel class of bacterial translation inhibitors, are described. Optimization was focused on the triazine C-4 position in which aromatic substituents that contained electron-withdrawing groups led to potent inhibitors. The initial lack of antibacterial activity was correlated with poor cellular penetration. Whole cell antibacterial activity was achieved by linking additional aromatic moieties at the triazine C-4 position.