91188-00-0

Basic information

• Product Name: CI 934
• Synonyms: CI 934;1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid;PD-114843;Aids007688;Aids-007688;Quinolone cl-934
• CAS NO: 91188-00-0
• Molecular Formula: C19H23 F2 N3 O3
• Molecular Weight: 379.4
• Mol File: 91188-00-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 545.8°Cat760mmHg
• Flash Point: 283.9°C
• Appearance: /
• Density: 1.304g/cm³
• CAS DataBase Reference: CI 934(CAS DataBase Reference)
• NIST Chemistry Reference: CI 934(91188-00-0)
• EPA Substance Registry System: CI 934(91188-00-0)

Safety Data

• Hazardous Substances Data: 91188-00-0(Hazardous Substances Data)

Upstream product

• 75338-42-0 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 
• 91187-83-6 3-((N-ethylamino)methyl)pyrrolidine 
• 100501-62-0 ethyl 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 79660-46-1 ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 

Relevant articles and documents

Antibacterial agents

Novel quinoline-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the antibacterial agents.

Process for quinoline-3-carboxylic acid antibacterial agents

An improved process for the preparation of 7-substituted amino-1-alkyl- or cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids is described where tetrafluorobenzoyl chloride is converted in three operations via 1-alkyl or 1-cycloalkyl-1

Process for quinoline-3-carboxylic acid antibacterial agents

An improved process for the preparation of 7-substituted amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids is described where an alkyl ester of a 6,7,8-trifluoro precursor is converted to a trialkylsilyl ester which fluorine at C7 is directly displaced to the desired product.