91222-91-2Relevant academic research and scientific papers
Diastereoselectivity of the CC Bond Formation Reaction of Cyclic Radicals
Giese, Bernd,Heuck, Klaus,Lenhardt, Herbert,Luening, Ulrich
, p. 2132 - 2139 (2007/10/02)
Solvomercuration and reductive CC bond formation reaction of cyclopentene, dihydrofuran, cyclohexene, and dihydropyran with alkenes 4 yield products 9-16.In these reactions the formation of trans-isomers predominantes (Tables 1-3).The stereoselectivity increases with decreasing reactivity of alkenes 4 and is greater with five-membered than six-membered rings.Dihydrofuran reacts with methyl acrylate to give trans- and cis-Isomers 11f and 12f in a 93:7 ratio (Table 2).In contrast, norbornene yields only the exo,cis-isomer 21.
