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2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE is a chemical compound that belongs to the class of thieno[2,3-d]pyrimidin-4(3H)-one derivatives. It contains a thieno[2,3-d]pyrimidin-4(3H)-one core with a chloromethyl group attached at the 2nd position and a 4-chlorophenyl group at the 5th position. 2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE is known for its structural properties and functional groups, making it a potential candidate for the development of drugs targeting specific biological pathways and diseases.

91225-69-3

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91225-69-3 Usage

Uses

Used in Organic Synthesis:
2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure and functional groups allow for the formation of new molecules with potential applications in different fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE is used as a key component in the development of new pharmaceuticals. Its structural properties make it a valuable asset in designing drugs that can target specific biological pathways and treat various diseases.
Used in Research and Development:
2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE is also utilized in research and development activities to study its pharmacological and toxicological properties. This helps in understanding its potential as a therapeutic agent and its safety profile for use in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 91225-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,2,2 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 91225-69:
(7*9)+(6*1)+(5*2)+(4*2)+(3*5)+(2*6)+(1*9)=123
123 % 10 = 3
So 91225-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H8Cl2N2OS/c14-5-10-16-12(18)11-9(6-19-13(11)17-10)7-1-3-8(15)4-2-7/h1-4,6H,5H2,(H,16,17,18)

91225-69-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(chloromethyl)-5-(4-chlorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:91225-69-3 SDS

91225-69-3Relevant academic research and scientific papers

Synthesis and biological evaluation of novel condensed pyrimidinylmethylsulfinylbenzimidazoles as antiulcer agent

Dudhe, Prashik B.,Jain, Kishor S.,Raskar, Vikas K.,Deodhe, Atul S.,Patel, Jasminkumar G.,Phoujdar, Manisha S.,Kathiravan, Muthu K.

, p. 3719 - 3727 (2013/07/26)

Current therapies to treat gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), and other acid-related diseases either prevent stimulation of the parietal cell (H2-receptor antagonists) or inhibit gastric H+/K+/s

Design, synthesis, and antihyperlipidemic evaluation of novel 2-[1-(Substitutedphenyl)-4-oxo-azetidin-2-yl]-5,6-disubstitutedthieno[2,3-d] pyrimidin-4(3H)-ones

Arya, Nikhilesh,Munde, Manoj K.,Dwivedi, Jaya,Jagdale, Archana Y.,Jain, Kishor S.

, p. 588 - 595 (2013/09/02)

Novel thienopyrimidine derivatives of azetidinone possessing the combined features of the cholesterol absorption inhibitor drug ezetimibe and potential antihyperlipidemic 2-substitutedthienopyrimidin-4-ones were synthesized and characterized by spectrosco

Synthesis and antihyperlipidemic activity of some novel condensed 2-chloroalkyl-4-chloro/hydroxy-5,6-disubstituted pyrimidines

Kathiravan, Matthu K.,Shishoo, Chamanlal J.,Kumar, Krishnan Girish,Roy, Saroj Kumar,Mahadik, Kakasheb R.,Kadam, Shivajirao S.,Jain, Kishor S.

, p. 599 - 606 (2008/03/13)

Synthesis and antihyperlipidemic activity of a series of novel condensed 2-chloroalkyl-4-chloro/hydroxy-5,6-di-substituted pyrimidines are described. The design of these compounds is based on the earlier QSAR study on the antihyperlipidemic 2-substituted

Reaction of Nitriles Under Acidic Conditions. Part III. A Facile Synthesis of Thienopyrimidin-4(3H)-ones

Shishoo, C. J.,Devani, M. B.,Pathak, U. S.,Ananthan, S.,Bhadti, V. S.,et al.

, p. 375 - 380 (2007/10/02)

A variety of thiophene o-aminoesters were reacted with cyanates, thiocyanates, cyanamides, acyl cyanides and α-functionalized acetonitrile derivatives to yield the corresponding 2-substituted thienopyrimidin-4(3H)-ones.

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