91228-41-0Relevant academic research and scientific papers
Enhanced reactivity of [hydroxy(tosyloxy)iodo]benzene in fluoroalcohol media. Efficient direct synthesis of thienyl(aryl)iodonium salts
Ito, Motoki,Ogawa, Chieko,Yamaoka, Nobutaka,Fujioka, Hiromichi,Dohi, Toshifumi,Kita, Yasuyuki
experimental part, p. 1918 - 1931 (2010/09/08)
In this manuscript, we report clear evidence for the generation of aromatic cation radicals produced by using [hydroxy(tosyloxy)iodo]benzene (HTIB) in fluoroalcohol solvents such as 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP). The single-electron-transfer (SET) oxidation ability of HTIB to give cation radicals was first established by ESR and UV measurements. The reaction was broadly applied to various thiophenes, and unique thienyliodonium salts were directly synthesized by this method in excellent yields without the production of any harmful byproducts.
Fluoroalcohols: Versatile solvents in hypervalent iodine chemistry and syntheses of diaryliodonium(III) salts
Dohi, Toshifumi,Yamaoka, Nobutaka,Kita, Yasuyuki
scheme or table, p. 5775 - 5785 (2010/09/14)
We first introduced 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) and 2,2,2-trifluoroethanol (TFE) as unique solvents for reactions involving hypervalent iodine-mediated phenolic oxidations in the 1980s, in which the fluoroalcohols have been successfully utili
Versatile direct dehydrative approach for diaryliodonium(III) salts in fluoroalcohol media
Dohi, Toshifumi,Ito, Motoki,Morimoto, Koji,Minamitsuji, Yutaka,Takenaga, Naoko,Kita, Yasuyuki
, p. 4152 - 4154 (2008/03/27)
We have found that the use of fluoroalcohol media greatly enhanced the efficiency and scope of the direct dehydrative condensation of arenes 1 and hypervalent iodine(iii) compounds; the present clean method has a broad range of applicability as well as un
