912335-92-3

Usage

Type of compound

Chemical compound

Derivative of

Azetidine-2-carboxylic acid (a naturally occurring amino acid found in certain types of plants)

Potential function

Inhibitor of enzymes involved in the biosynthesis of peptidoglycan (an essential component of bacterial cell walls)

Studied for

Potential antibacterial properties

Modification

Addition of the benzyloxy carbonyl group to the azetidine-2-carboxylic acid molecule

Impact of modification

May affect biological activity and make it a potential candidate for pharmaceutical applications

Further research

Needed to fully understand the properties and potential uses of 1-[(benzyloxy)carbonyl]-2-methylazetidine-2-carboxylic acid

Upstream product

• 1013038-78-2 C₁₄H₁₇NO₄ 
• 912335-91-2 dibenzyl 2-methylazetidine-1,2-dicarboxylate 

Downstream Products

• 912335-93-4 benzyl 2-({[2-amino-3-(aminocarbonyl)phenyl]amino}carbonyl)-2-methylazetidine-1-carboxylate 
• 942203-07-8 C₁₇H₂₃N₃O₄ 
• 1013038-62-4 C₁₇H₂₂N₂O₅ 

Relevant academic research and scientific papers

Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn induction

(Figure Presented) The influence of 2-alkyl-2-carboxyazetidines (Aze) on the 3D structure of model tetrapeptides R2CO-2-R1Aze-L- Ala-NHMe has been analyzed by molecular modeling, 1H NMR, and FT-IR studies. The conformation

1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors

Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of For

2-Substituted-1 H-benzimidazile-4-carboxamides are PARP inhibitors

Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), method of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compound of Formula (I).