942203-07-8Relevant articles and documents
Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn induction
Baeza, Jose Luis,Gerona-Navarro, Guillermo,De Vega, M. Jesus Perez,Garcia-Lopez, M. Teresa,Gonzalez-Muniz, Rosario,Martin-Martinez, Mercedes
, p. 1704 - 1715 (2008/09/20)
(Figure Presented) The influence of 2-alkyl-2-carboxyazetidines (Aze) on the 3D structure of model tetrapeptides R2CO-2-R1Aze-L- Ala-NHMe has been analyzed by molecular modeling, 1H NMR, and FT-IR studies. The conformation
2-Alkyl-2-carboxy-azetidines as scaffolds for the induction of γ-turns
Baeza, José Luis,Gerona-Navarro, Guillermo,Pérez de Vega, Ma Jesús,García-López, Ma Teresa,González-Mu?iz, Rosario,Martín-Martínez, Mercedes
, p. 3689 - 3693 (2008/02/03)
To investigate the ability of 2-alkyl-2-carboxy-azetidines (Azx) to induce reverse turns when incorporated into peptides, RCO-Azx-l-Ala-NHMe dipeptide derivatives were selected as simplified tetrapeptide models, in which the azetidine residue is incorpora