912346-76-0

Basic information

• Product Name: (3R,4R,5S)-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-((R)-1-oxiranyl-methoxy)-piperidine-1-carboxylic acid benzyl ester
• Synonyms: (3R,4R,5S)-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-((R)-1-oxiranyl-methoxy)-piperidine-1-carboxylic acid benzyl ester
• CAS NO: 912346-76-0
• Molecular Weight: 690.834
• Mol File: 912346-76-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,4R,5S)-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-((R)-1-oxiranyl-methoxy)-piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5S)-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-((R)-1-oxiranyl-methoxy)-piperidine-1-carboxylic acid benzyl ester(912346-76-0)
• EPA Substance Registry System: (3R,4R,5S)-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-((R)-1-oxiranyl-methoxy)-piperidine-1-carboxylic acid benzyl ester(912346-76-0)

Safety Data

• Hazardous Substances Data: 912346-76-0(Hazardous Substances Data)

Upstream product

• 912346-67-9 (3S,4S,5R)-3-hydroxy-4-[4-(2-methoxy-ethoxymethyl)-phenyl]-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-piperidine-1-carboxylic acid benzyl ester 
• 113826-06-5 (R)-glycidyl tosylate 

Relevant articles and documents

Organic compounds

The present invention relates to substituted piperidines of the general formula (I), where R1, R2, R3, R4, R5, Q and X have the definitions elucidated in more detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors. Moreover, the enzymatic substrate portion of the compound is simultaneously a substrate for a membrane transporter.