91252-41-4Relevant academic research and scientific papers
Novel α1- adrenergic receptor agonists
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, (2018/07/31)
The present invention relates to a novel andalpha;1-adrenergic receptor agonist, and more particularly, to a novel analogue of midodrine which is andalpha;1-adrenergic receptor agonist. The midodrine analogue of the present invention increase an expression of p-AMPK, PPARanddelta;, PGC-1andalpha;, which are essential for maintaining and regulating in vivo energy metabolism activity, thereby being usefully used for preventing or treating diseases (such as metabolic diseases, cardiovascular diseases, inflammatory diseases, etc.) in which activation of AMPK is required.COPYRIGHT KIPO 2018
MORPHOLINE DOPAMINE AGONISTS FOR THE TREATMENT OF PAIN
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Page/Page column 40, (2008/12/07)
The present invention relates to use of a compound of formula (I), (Ia), or (Ib), wherein A, B, Z, R1and R2 have the meanings given in the specification, as a medicament for the treatment of a number of pain conditions, particularly chronic or nociceptive
MORPHOLINE DERIVATIVES FOR USE AS DOPAMINE AGONISTS IN THE TREATMENT OF I.A. SEXUAL DYSFUNCTION
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Page 68-69, (2008/06/13)
The present invention provides for compounds of formula (I), (la) and (lb) Wherein: A is selected from C-X and N, B is selected from C-Y and N, R1 is selected from H and (C1-C6)alkyl R2 is selected from H and (C
