912539-32-3

Upstream product

• 912539-31-2 [4-(5-amino-4-carbamoyl-imidazol-1-yl)-phenyl]-carbamic acid tert-butylester 

Downstream Products

• 912539-33-4 C₁₆H₁₈N₆O₂ 
• 863675-87-0 9-(4-aminophenyl)purin-6-amine 

Relevant academic research and scientific papers

Pyrazole Derivatives Having Tyrosine Kinase Activity

Compounds of the formula (I), in which R, X, R1, R2, R3 and R4 have the meanings indicated in Claim (1), are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia,

PURINE DERIVATIVES AS RECEPTOR-TYROSINE KINASE ACTIVITYINHIBITORS

The invention relates to compounds of formula (I), whereon R1, R2, R3, R4 and X have the meanings cited in claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and the Raf-kinases and can be also be used for treating tumours.