912646-24-3

Upstream product

• 167640-30-4 (αR,α'R,4R,5R)-2,2,α,α'-tetramethyl-α,α'-diphenyl-1,3-dioxolane-4,5-dimethanol 
• 74-88-4 methyl iodide 
• 177283-77-1 (4R,5R)-N,N'-dimethoxy-N,N',2,2-tetramethyl-1,3-dioxolane-4,5-dicarboxamide 
• 88244-50-2 3,4-O-isopropylidene-(3R,4R)-3,4-dihydroxyhexane-2,5-dione 

Downstream Products

• 91899-79-5 (S)-2-methoxy-2-phenylpropanal 
• 24190-08-7 (R)-(-)-2-methoxy-2-phenylpropionic acid 
• 912646-25-4 (2R,3R,4R,5R)-2,5-dimethoxy-2,5-diphenylhexane-3,4-diol 

Relevant academic research and scientific papers

Asymmetric synthesis of both enantiomers of α-methyl-α-methoxyphenylacetic acid from l-(+)-tartaric acid: formal enantioselective synthesis of insect pheromone (-)-frontalin

Both antipodes of α-methyl-α-methoxyarylacetic acid derivatives were prepared from a common chiralpool precursor l-(+)-tartaric acid. The key step involves the addition of Grignard reagents to 1,4-diketones derived from tartaric acid. The utility of this