912677-66-8Relevant articles and documents
Synthesis and trypanocidal activity of 1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol
Bernardes, Lilian Sibelle Campos,Kato, Massuo Jorge,Albuquerque, Sergio,Carvalho, Ivone
, p. 7075 - 7082 (2006)
Chagas' disease is endemic in Central and South American countries. Specific chemotherapy with nifurtimox or benznidazole has been recommended for treatment of recent infection but they have limited efficacy. The natural products veraguensin (1) and grand