912756-16-2Relevant academic research and scientific papers
Enantioselective synthesis of tetrahydropyrano[3,4- b ]indoles catalyzed by chiral N -triflyl phosphoramide via intramolecular friedel-crafts alkylation reaction
Zhang, Jun-Wei,Cai, Quan,Shi, Xiao-Xin,Zhang, Wei,You, Shu-Li
supporting information; experimental part, p. 1239 - 1242 (2011/07/06)
A highly efficient intramolecular enantioselective Friedel-Crafts alkylation reaction of indolyl enones utilizing chiral N-triflyl phosphoramide catalyst is described. Various tetrahydropyrano[3,4-b]indoles (THPI) have been afforded with excellent yields and up to 98% ee. Georg Thieme Verlag Stuttgart - New York.
