912757-65-4Relevant academic research and scientific papers
The conjugation of rhodamine B enables carrier-free mitochondrial delivery of functional proteins
Ding, Feng,Huang, Hua,Li, Xiang,Liu, Changlin,Liu, Nian,Shi, Jiayuan,Tang, Xuemei,Zhao, Dan
, p. 6829 - 6839 (2020)
The development of protein-based therapeutics faces many challenges, for example, carrier-dependence, safety concerns, endocytosis-dependence, and uncertain in vivo therapeutic outcomes. Small molecules are rarely used for intracellular organelle-targetin
N-terminal protein modification through a biomimetic transamination reaction
Gilmore, Joshua M.,Scheck, Rebecca A.,Esser-Kahn, Aaron P.,Joshi, Neel S.,Francis, Matthew B.
, p. 5307 - 5311 (2007/10/03)
(Chemical Equation Presented) One hit wonder: A biomimetic transamination reaction has been developed that employs pyridoxal-5-phosphate to modify the N terminus of proteins and peptides under mild conditions. This technique introduces a uniquely reactive
