912849-66-2Relevant academic research and scientific papers
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification
Meier, Jordan L.,Mercer, Andrew C.,Rivera Jr., Heriberto,Burkart, Michael D.
, p. 12174 - 12184 (2006)
In vivo carrier protein tagging has recently become an attractive target for the site-specific modification of fusion systems and new approaches to natural product proteomics. A detailed study of pantetheine analogues was performed in order to identify su
Visualizing the chain-flipping mechanism in fatty-acid biosynthesis
Beld, Joris,Cang, Hu,Burkart, Michael D.
, p. 14456 - 14461 (2015/02/19)
The acyl carrier protein (ACP) from fatty acid synthases sequesters elongating products within its hydrophobic core, but this dynamic mechanism remains poorly understood. We exploited solvatochromic pantetheine probes attached to ACP that fluoresce when s
