91285-33-5

Upstream product

• 57000-13-2 8-(benzylamino)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 
• 96-32-2 bromoacetic acid methyl ester 
• 91285-01-7 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione 

Downstream Products

• 91285-16-4 9-benzyl-1,3-dimethyl-6-hydroxy-7-(2-hydroxyethyl)pyrimido<2,1-f>purine-2,4,8(1H,3H,9H)-trione 
• 114927-80-9 9-benzyl-1,3-dimethyl-6-hydroxy-7-(2-hydroxyethyl)pyrimido<2,1-f>purine-4,8(1H,9H)-dione 

Relevant academic research and scientific papers

Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones

Substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones their tautomers and salts are anti-inflammatory agents. Methods for their preparation and use are described.

REGIOSPECIFIC ALKYLATION OF 9-BENZYL-1,3-DIMETHYL-6-HYDROXYPYRIMIDOPURINE-2,4,8(1H,3H,9H)-TRIONE

The sodium salt of 9-benzyl-1,3-dimethyl-6-hydroxypyrimidopurine-2,4,8(1H,3H,9H)-trione (1a) reacted with a series of alkyl halides in N,N-dimethylformamide to yield 7-carbon alkylated products (1b-1).No O-alkylated products were detected.Isolated