91285-72-2

Upstream product

• 91285-68-6 (4S,6R)-4-(2-benzyloxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 
• 23402-69-9 lithium diphenylcuprate 
• 152419-73-3 Acetic acid 2-{(4S,6R)-2,2-dimethyl-6-[2-(toluene-4-sulfonyloxy)-ethyl]-[1,3]dioxan-4-yl}-ethyl ester 
• 152419-65-3 7-Benzyloxy-5-hydroxy-3-oxo-heptanoic acid methyl ester 
• 146367-50-2 (4R,6S)-2,2-dimethyl-1,3-dioxane-4,6-diyl-bis-ethane-2,1-diyl diacetate 
• 146367-51-3 2-((4S,6R)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl)ethyl acetate 
• 146367-49-9 2,2'-((4R,6S)-2,2-dimethyl-1,3-dioxane-4,6-diyl)bis(ethan-1-ol) 
• 146367-52-4 (4S,6R)-4-(2-acetoxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 91285-71-1 tert-Butyl-[2-((4S,6R)-2,2-dimethyl-6-phenethyl-[1,3]dioxan-4-yl)-ethoxy]-diphenyl-silane 
• 465545-21-5 (4S,6R)-4-(2-(tert-butyldimethylsilyloxy)-ethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 

Downstream Products

• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 
• 91285-68-6 (4S,6R)-4-(2-benzyloxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 465545-31-7 (4S,6R)-4-(O-mesyl-2-hydroxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 146367-52-4 (4S,6R)-4-(2-acetoxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 

Relevant academic research and scientific papers

Empirical model for the molar rotations of syn-2,2-dimethyl-1,3-dioxanes.

[structure: see text] A useful method for the prediction of molar rotation ([Phi]) of syn-2,2-dimethyl-1,3-dioxanes (acetonides) is described. A series of acetonides were prepared by standard methods. A simple additive relationship between the substituent

Enzyme-catalyzed desymmetrization of meso-skipped polyols to useful chiral building blocks

The biocatalytic desymmetrization, in presence of different enzymes, of two models of polyfunctionalized diols in a meso form was studied. PFL was found to be the most selective enzyme with excellent results in chemical and optical yield with some of the tested substrates. The obtained chiral building block was utilized for some useful synthetic transformations toward the synthesis of natural products.

SYNTHETIC STUDIES RELATED TO COMPACTIN AND MEVINOLIN: A NEW SYNTHESIS OF THE LACTONE SYSTEM.

(S)-Malic acid diethyl ester was converted into a precursor of the lactonic portion of compactin and mevinolin.The substance was coupled with benzyl p-tolyl sulfone and elaborated into the chiral lactone system of the natural products.