91285-71-1

Upstream product

• 485321-78-6 methanesulfonic acid 4-(tert-butyl-diphenyl-silanyloxy)-2-trityloxy-butyl ester 
• 485321-77-5 4-(tert-butyl-diphenyl-silanyloxy)-2-trityloxy-butan-1-ol 
• 485321-79-7 4-(tert-butyl-diphenyl-silanyloxy)-1-(2-phenethyl-[1,3]dithian-2-yl)-butan-2-ol 
• 485321-80-0 7-(tert-butyl-diphenyl-silanyloxy)-5-hydroxy-1-phenyl-heptan-3-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 116996-53-3 Methanesulfonic acid (S)-4-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-butyl ester 
• 125975-53-3 (2S)-O-(tert-butyldiphenylsilyl)-1,2-epoxybutan-4-ol 
• 77-76-9 2,2-dimethoxy-propane 
• 91285-70-0 (3S,5R)-1-(tert-Butyl-diphenyl-silanyloxy)-7-phenyl-heptane-3,5-diol 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 
• 67-64-1 acetone 

Downstream Products

• 91285-72-2 (4S,6R)-4-(2-hydroxyethyl)-6-(2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 

Relevant academic research and scientific papers

First total synthesis and determination of the absolute configuration of strictifolione, a new 6-(ω-phenylalkenyl)-5,6-dihydro-α-pyrone, isolated from Cryptocarya strictifolia

Starting from (S)-malic acid and (S)-glycidol, the first total synthesis of strictifolione, a new 6-(ω-phenylalkenyl)-5,6-dihydro-α-pyrone isolated from Cryptocarya strictifolia, was accomplished, which confirmed its structure including the absolute confi

SYNTHETIC STUDIES RELATED TO COMPACTIN AND MEVINOLIN: A NEW SYNTHESIS OF THE LACTONE SYSTEM.

(S)-Malic acid diethyl ester was converted into a precursor of the lactonic portion of compactin and mevinolin.The substance was coupled with benzyl p-tolyl sulfone and elaborated into the chiral lactone system of the natural products.