91304-86-8Relevant academic research and scientific papers
TRIMETHYLSILYL TRIFLUORMETHANESULFONATE (TRIMETHYLSILYL TRIFLATE) AS AN EXCELLENT GLYCOSIDATION REAGENT FOR ANTHRACYCLINE SYNTHESIS. SIMPLE AND EFFICIENT SYNTHESIS OF OPTICALLY PURE 4-DEMETHOXYDAUNORUBICIN
Kimura, Yoshikazu,Suzuki, Michiyo,Matsumoto, Teruyo,Abe, Rumiko,Terashima, Shiro
, p. 501 - 504 (1984)
The title reagent was found to effect the glycosidation of (+)-4-demethoxyanthracyclinones with N-trifluoracetyl-1,4-di-O-p-nitrobenzoyl-L-daunosamine, giving the α-glycosides in 99percent yields.Sequential deprotections of the glycoside readily afforded optically pure (+)-4-demethoxydaunorubicin.
