913093-77-3

Upstream product

• 97643-04-4 2,2-dimethyl-3(R)-hydroxy-5(R)-isopropylenecyclohexanone 
• 913093-74-0 (1R,3R,5R)-5-isopropenyl-2,2-dimethyl-1-vinylcyclohexane-1,3-diol 
• 913093-76-2 (3S,5S)-3-hydroxy-5-isopropenyl-2,2-dimethyl-3-[(2R)-oxiran-2-yl]cyclohexanone 
• 108-98-5 thiophenol 

Downstream Products

• 913093-78-4 (2S,4S,5S,9S)-9-isopropenyl-6,6-dimethyl-2-phenyl-4-[(phenylthio)methyl]-1,3-dioxaspiro[4.5]decan-7-one 
• 913093-91-1 2-{4-[(2S,4S,5S,9R)-9-(tert-Butyl-dimethyl-silanyloxy)-4-((E)-3-hydroxy-propenyl)-6,6,8-trimethyl-2-phenyl-1,3-dioxa-spiro[4.5]dec-7-en-7-yl]-2-methyl-3-oxo-butyl}-malonic acid dimethyl ester 
• 913093-97-7 2-{4-[(2S,4S,5S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-4-((E)-3-hydroxy-propenyl)-6,6,8-trimethyl-2-phenyl-1,3-dioxa-spiro[4.5]dec-7-en-7-yl]-2-methyl-3-oxo-butyl}-malonic acid dimethyl ester 
• 913093-92-2 dimethyl (4-{(2S,4S,5S,9R)-9-[tert-butyl(dimethyl)silyloxy]-4-[(1E)-3-chloroprop-1-en-1-yl]-6,6,8-trimethyl-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-7-yl}-2-methyl-3-oxobutyl)malonate 
• 913093-90-0 1-{(2S,4S,5S,9R)-9-[tert-butyl(dimethyl)silyloxy]-4-[(1E)-3-hydroxyprop-1-en-1-yl]-6,6,8-trimethyl-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-7-yl}-3-methylbut-3-en-2-one 
• 913093-96-6 1-{(2S,4S,5S,9S)-9-[tert-butyl(dimethyl)silyloxy]-4-[(1E)-3-hydroxyprop-1-en-1-yl]-6,6,8-trimethyl-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-7-yl}-3-methylbut-3-en-2-one 
• 913093-89-7 (2E)-3-{(2S,4S,5S,9R)-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-7-(3-methyl-2-oxobut-3-en-1-yl)-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}acrylaldehyde 
• 913093-95-5 (2E)-3-{(2S,4S,5S,9S)-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-7-(3-methyl-2-oxobut-3-en-1-yl)-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}acrylaldehyde 
• 913093-87-5 {(2S,4S,5S,9R)-7-allyl-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}methyl acetate 
• 913093-75-1 {(2S,4S,5S,9S)-7-allyl-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}methyl acetate 
• 913093-88-6 {(2S,4S,5S,9R)-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-7-(2-oxoethyl)-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}methyl acetate 
• 913093-84-2 {(2S,4S,5S,9S)-9-[tert-butyl(dimethyl)silyloxy]-6,6,8-trimethyl-7-(2-oxoethyl)-2-phenyl-1,3-dioxaspiro[4.5]dec-7-en-4-yl}methyl acetate 
• 913093-80-8 (2S,4S,5S,8R,9S)-9-isopropenyl-6,6,8-trimethyl-2-phenyl-4-[(phenylsulfinyl)methyl]-1,3-dioxaspiro[4.5]decan-7-one 

Relevant academic research and scientific papers

Novel synthetic strategy towards taxol by macrocyclization reaction - Conformational requirement of ring A

The synthesis of a completely substituted ring A of Taxol is reported and it is shown that the C13-OP group must have a β configuration to succeed in the formation of 12-membered rings, a requisite for the construction of the B and C rings of T