91324-97-9Relevant academic research and scientific papers
N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-allergic use thereof
-
, (2008/06/13)
Novel 4-acylresorcinol ethers of the formula STR1 in which R1 is lower alkyl, alk is a hydroxyalkylene radical which can be interrupted by oxygen and R2 is 5-tetrazolyl, it being possible for the ring A to be additionally substituted
Leucotriene antagonists
-
, (2008/06/13)
The compounds STR1 wherein each X is, independently, --O-- or --NR5, in which R5 is hydrogen or alkyl; R is alkyl, R1 is hydrogen or alkyl, R2 is hydrogen, hydroxy, amino, alkylamino, dialkylamino or alkanoylamino and when m or n is O, R2 is hydroxymethyl, aminomethyl, alkylaminomethyl, dialkylaminomethyl or alkanoylaminomethyl; R3 is hydrogen, --CN, --CONH2 or --CO2 M in which M is hydrogen, alkyl or STR2 in which p is an integer from 2 to 6 and R6 and R7 are, independently, hydrogen or alkyl; R4 is --NH2, --NHCOR8 in which R8 is alkyl, --NHCOCO2 Z or --NHCOCH2 CH2 CO2 Z in which Z is hydrogen or alkyl; m and n are 0, 1, 2, 3 or 4 such that when n is from 1 to 4, m is 0 or 1 and when m is from 1 to 4, n is 0 or 1; or pharmaceutically acceptable salts thereof are leucotriene antagonists useful as antiallergy agents.
