913373-34-9Relevant academic research and scientific papers
Discovery of New 2-[(4,6-Dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(substituted phenoxy)benzoic Acids as Flexible Inhibitors of Arabidopsis thaliana Acetohydroxyacid Synthase and Its P197L Mutant
Qu, Ren-Yu,Yang, Jing-Fang,Devendar, Ponnam,Kang, Wei-Ming,Liu, Yu-Chao,Chen, Qiong,Niu, Cong-Wei,Xi, Zhen,Yang, Guang-Fu
, p. 11170 - 11178 (2018/01/10)
In the search for new antiresistance acetohydroxyacid synthase (AHAS, EC 2.2.1.6) inhibitors to combat weed resistance associated with AHAS mutations, a series of 2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(substituted phenoxy)benzoic acids 11-38 were de
Metal-free synthesis of ortho -CHO diaryl ethers by a three-component sequential coupling
Liu, Fangliang,Yang, Huameng,Hu, Xinquan,Jiang, Gaoxi
supporting information, p. 6408 - 6411 (2015/01/09)
A practical, metal-free, and highly chemoselective approach was developed for the synthesis of ortho-CHO diaryl ethers by a three-component sequential coupling of arynes, N,N-dimethylformamide (DMF), and diaryliodonium salts. Diverse functional groups including halo, nitryl, and bulky substituents and heteroaromatics are well tolerated. Mechanistically, isotopic tracer experiments reveal that the diaryliodonium salt serves as an electrophile to trap the transient intermediates generated from the [2 + 2] cyclization of an aryne and DMF.
Intramolecular 1,3-dipolar cycloaddition of nitrile N-oxide accompanied by dearomatization
Yonekawa, Morio,Koyama, Yasuhito,Kuwata, Shigeki,Takata, Toshikazu
supporting information; experimental part, p. 1164 - 1167 (2012/03/27)
Intramolecular 1,3-dipolar cycloaddition of 2-phenoxybenzonitrile N-oxides to benzene rings, accompanied by dearomatization, formed the corresponding isoxazolines in high yields. The X-ray single-crystal structure analysis revealed that the reaction formed the cis-adduct as a single isomer. The substituents on the benzene rings markedly affected the reaction rate, yield, and structure of the final product.
