913566-66-2Relevant academic research and scientific papers
Nonracemic bicyclic lactam lactones via regio- and cis-diastereocontrolled C-H insertion. Asymmetric synthesis of (8S,8aS)-octahydroindolizidin-8-ol and (1S,8aS)-octahydroindolizidin-1-ol
Wee, Andrew G. H.,Fan, Gao-Jun,Bayirinoba, Hypolite M.
experimental part, p. 8261 - 8271 (2010/02/17)
(Chemical Equation Presented) The Rh2(MPPIM)4- catalyzed intramolecular C-H insertion reaction of (S)- and (R)-1-benzyl-5-(R- diazoacetoxy)piperidin-2-one and (S)-1-benzyl-4-(α-diazoacetoxy) pyrrolidin-2-one proceeds with high regios
Asymmetric synthesis of (+)-isofebrifugine and (-)-sedacryptine from a common chiral nonracemic building block
Wee, Andrew G. H.,Fan, Gao-Jun
scheme or table, p. 3869 - 3872 (2009/07/01)
(Chemical Equation Presented) The stereoselective syntheses of 2-substituted and 2,6-disubstituted 3-hydroxypiperidine alkaloids, (+)-isofebrifugine and (-)-sedacryptine, from a common, functionalized nonracemic bicyclic building block are achieved, demon
Regio- and diastereocontrolled C-H insertion of chiral γ- and δ-lactam diazoacetates. Application to the asymmetric synthesis of (8S,8aS)-8-hydroxyindolizidine
Fan, Gao-Jun,Wang, Zhongyi,Wee, Andrew G. H.
, p. 3732 - 3734 (2007/10/03)
γ- and δ-Lactam diazoacetates undergo efficient intramolecular C-H insertion catalyzed by Rh2(MPPIM)4 with excellent regioselectivity and cis-diastereoselectivity to provide synthetically useful bicyclic lactam lactones. The Royal So
