913569-73-0Relevant articles and documents
Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy
Hall, Adrian,Billinton, Andy,Brown, Susan H.,Clayton, Nicholas M.,Chowdhury, Anita,Giblin, Gerard M.P.,Goldsmith, Paul,Hayhow, Thomas G.,Hurst, David N.,Kilford, Ian R.,Naylor, Alan,Passingham, Barry,Winyard, Lisa
, p. 3392 - 3399 (2008)
Replacement of the carboxylic acid group in a series of previously described methylene-linked pyrazole EP1 receptor antagonists led to the discovery of amide, reversed amide and carbamate derivatives. Two compounds, 10a and 10b, were identified