913567-99-4Relevant articles and documents
Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy
Hall, Adrian,Billinton, Andy,Brown, Susan H.,Clayton, Nicholas M.,Chowdhury, Anita,Giblin, Gerard M.P.,Goldsmith, Paul,Hayhow, Thomas G.,Hurst, David N.,Kilford, Ian R.,Naylor, Alan,Passingham, Barry,Winyard, Lisa
scheme or table, p. 3392 - 3399 (2009/04/06)
Replacement of the carboxylic acid group in a series of previously described methylene-linked pyrazole EP1 receptor antagonists led to the discovery of amide, reversed amide and carbamate derivatives. Two compounds, 10a and 10b, were identified
PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS
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, (2008/06/13)
Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein Z, R1 ,R2a, R2b, R10, R11 and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.