91359-44-3

Upstream product

• 91359-43-2 1,2-Dibrom-3-oxo-3-phenyl-1-propyl-phosphonsaeure-diethylester 
• 131719-45-4 diethyl 3-phenylprop-2-yn-1-ylphosphonate 
• 4851-51-8 diethyl ethynylphosphonate 
• 98-88-4 benzoyl chloride 
• 70508-77-9 diethyl (E)-(3-oxo-3-phenylprop-1-en-1-yl)phosphonate 

Downstream Products

• 91359-54-5 3-Benzoyl-4-pyrazolyl-phosphonsaeure-diethylester 
• 1392492-84-0 diethyl 5-phenyl-1H-pyrazol-3-yl-3-phosphonate 

Relevant academic research and scientific papers

Selenium-π-Acid Catalyzed Oxidative Functionalization of Alkynes: Facile Access to Ynones and Multisubstituted Oxazoles

Unprecedented selenium-catalyzed propargylic oxidation of alkynes is disclosed. Various propargylphosphonates and 3-alkynoates were efficiently converted to valuable ynones via unusual C-C triple bond migration and deselenenylation at a vinyl carbon. By the strategies of tautomerization of enamine intermediate and SN2 displacement, similar conditions were effective for the oxidative difunctionalization of ynamides to afford multisubstituted oxazoles with high regioselectivity. Mechanistic studies revealed these detailed processes.

A convenient one-pot two-step synthesis of pyrazolylphosphonates from ethynylphosphonate

A convenient one-pot preparation of pyrazol-3-ylphosphonates involves Cu-catalyzed cross-coupling of acyl chlorides with diethyl ethynylphosphonate followed by heterocyclization with hydrazine.