913734-73-3

Upstream product

• 913734-69-7 tert-butyl 4-(2-(2-fluoroethoxy)phenyl)piperazine-1-carboxylate 
• 110-85-0 piperazine 
• 825-65-0 2-Chlorophenyl 2-fluoroethyl ether 
• 1011-17-2 2-hydroxyphenylpiperazine 

Downstream Products

• 1351409-39-6 2-(4-{4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl}butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione 
• 1314032-23-9 7-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one 
• 1016167-61-5 C₂₀H₂₃FN₄O 
• 1016167-57-9 C₂₀H₂₃FN₄O 

Relevant academic research and scientific papers

Pd-Catalyzed Synthesis of Piperazine Scaffolds under Aerobic and Solvent-Free Conditions

A facile Pd-catalyzed methodology providing an efficient synthetic route to biologically relevant arylpiperazines under aerobic conditions is reported. Electron donating and sterically hindered aryl chlorides were aminated to afford yields up to 97%, with examples using piperazine as solvent, illustrating an ecofriendly, cost-effective synthesis of these privileged structures.

Synthesis of novel WAY 100635 derivatives containing a norbornene group and radiofluorination of [18F]AH1.MZ as a serotonin 5-HT1A receptor antagonist for molecular imaging

5-HT1A receptors are involved in a variety of psychiatric disorders and in vivo molecular imaging of the 5-HT1A status represents an important approach to analyze and treat these disorders. We report herein the synthesis of three new

Syntheses and radiofluorination of two derivatives of 5-cyano-indole as selective ligands for the dopamine subtype-4 receptor

Two fluoroethoxy substituted derivatives, namely 2-[4-(2-(2-fluoroethoxy) phenyl)-piperazin-1-ylmethyl]indole-5-carbonitrile (5a) and 2-[4-(4-(2- fluoroethoxy)-phenyl) piperazin-1-ylmethyl]indole-5-carbonitrile (Sb) were synthesized as analogs of the sele