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2-Chlorophenyl 2-fluoroethyl ether is an organic compound with the chemical formula C8H8ClFO. It is a colorless liquid at room temperature and has a molecular weight of 174.60 g/mol. This ether derivative features a 2-chlorophenyl group (a benzene ring with a chlorine atom at the 2nd position) and a 2-fluoroethyl group (an ethyl group with a fluorine atom at the 2nd position) connected by an oxygen atom. The compound is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of selective serotonin reuptake inhibitors (SSRIs) and other antidepressant medications. Due to its potential reactivity and the presence of a chlorine atom, it is essential to handle 2-chlorophenyl 2-fluoroethyl ether with caution and proper safety measures.

825-65-0

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825-65-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 825-65-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,2 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 825-65:
(5*8)+(4*2)+(3*5)+(2*6)+(1*5)=80
80 % 10 = 0
So 825-65-0 is a valid CAS Registry Number.

825-65-0Relevant academic research and scientific papers

Pd-Catalyzed Synthesis of Piperazine Scaffolds under Aerobic and Solvent-Free Conditions

Reilly, Sean W.,Mach, Robert H.

, p. 5272 - 5275 (2016)

A facile Pd-catalyzed methodology providing an efficient synthetic route to biologically relevant arylpiperazines under aerobic conditions is reported. Electron donating and sterically hindered aryl chlorides were aminated to afford yields up to 97%, with examples using piperazine as solvent, illustrating an ecofriendly, cost-effective synthesis of these privileged structures.

Pesticidal 2-fluoroethyl ethers

-

, (2008/06/13)

Pesticidal mono-, di-, and tri-2-fluoroethyl ethers of the formula R1 R2m Ar(OCH2 CH2 F)n, compositions thereof and their insecticidal, acaricidal and nematicidal uses are described and cla

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