913849-60-2Relevant academic research and scientific papers
Construction of Bisbenzopyrone via N-Heterocyclic Carbene Catalyzed Intramolecular Hydroacylation-Stetter Reaction Cascade
Zhao, Ming,Liu, Jia-Lin,Liu, Hang-Fan,Chen, Jie,Zhou, Ling
, p. 2676 - 2679 (2018)
An efficient synthesis of bisbenzopyrones by a N-heterocyclic carbene (NHC)-catalyzed intramolecular hydroacylationaStetter reaction cascade has been developed. A series of symmetrical and unsymmetrical bisbenzopyrones were obtained with good to excellent
Ring-closing metathesis reaction-based synthesis of new classes of polyether macrocyclic systems
Naveen,Babu, Srinivasarao Arulananda
supporting information, p. 7758 - 7781 (2015/09/08)
Ring closing metathesis (RCM) reactions of suitable substrates having terminal olefins, which are assembled from various linkers and hydroxy benzaldehydes and syntheses of a wide range of 16-30 membered, new crown ether-type polyether, aza-polyether, bis aza-polyether macrocycles and dilactone moiety embedded polyether macrocycles (macrolides) are reported. After the ring-closure reaction, installation of different functional groups and functional group modification on the periphery of the synthesized polyether/crown ether macrocycles obtained in the RCM reactions are accomplished using the epoxidation, oxidation and catalytic hydrogenation-based synthetic transformations. Along this line, the syntheses of a variety of polyether macrocycles possessing epoxide or α-hydroxy ketone or 1,2-diol functionalities at the periphery have been shown. Furthermore, the synthesized α-hydroxy ketone functionality installed polyether macrocycles were subjected to the allylation and Reformatsky type reactions to obtain homoallyl alcohol moiety-based and lactone ring-appended polyether macrocycles.
