913949-87-8

Basic information

• Product Name: 4-((S)-4-tert-butoxycarbonyl-2-{[6-(3-hydroxy-piperidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester
• CAS NO: 913949-87-8
• Molecular Weight: 624.737
• Mol File: 913949-87-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((S)-4-tert-butoxycarbonyl-2-{[6-(3-hydroxy-piperidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((S)-4-tert-butoxycarbonyl-2-{[6-(3-hydroxy-piperidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester(913949-87-8)
• EPA Substance Registry System: 4-((S)-4-tert-butoxycarbonyl-2-{[6-(3-hydroxy-piperidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester(913949-87-8)

Safety Data

• Hazardous Substances Data: 913949-87-8(Hazardous Substances Data)

Upstream product

• 710335-28-7 4-((S)-2-amino-4-tert-butoxycarbonyl-butyryl)piperazine-1-carboxylic acid ethyl ester 
• 913952-59-7 6-chloro-2-phenylpyrimidine-4-carboxylic acid 
• 325685-59-4 4-chloro-6-methoxymethyl-2-phenylpyrimidine 
• 339278-89-6 6-methoxymethyl-2-phenylpyrimidin-4-ol 
• 1148122-15-9 6-chloro-2-phenylpyrimidine-4-carbonyl chloride 
• 618-39-3 benzamidin 
• 325685-75-4 4-Chloro-6-hydroxymethyl-2-phenylpyrimidine 
• 710335-29-8 ethyl 4-((2S)-2-([(benzyloxy)carbonyl]amino)-5-tert-butoxy-5-oxopentanoyl)piperazine-1-carboxylate 
• 3886-08-6 5-tert-butyl N-benzyloxycarbonyl-L-glutamate 
• 120-43-4 4-ethoxycarbonylpiperazine 
• 6859-99-0 3-hydroxypiperazine 
• 913952-88-2 4-{(S)-4-tert-butoxycarbonyl-2-[(6-chloro-2-phenyl-pyrimidine-4-carbonyl)-amino]-butyryl}-piperazine-1-carboxylic acid ethyl ester 

Downstream Products

• 913949-43-6 4-((S)-4-carboxy-2-{[6-(3-hydroxy-piperidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y12 antagonists for inhibition of platelet aggregation

2-Phenyl-pyrimidine-4-carboxamide analogs were identified as P2Y 12 antagonists. Optimization of the carbon-linked or nitrogen-linked substituent at the 6-position of the pyrimidine ring provided compounds with excellent ex vivo potency in the