913951-70-9

Upstream product

• 913952-88-2 4-{(S)-4-tert-butoxycarbonyl-2-[(6-chloro-2-phenyl-pyrimidine-4-carbonyl)-amino]-butyryl}-piperazine-1-carboxylic acid ethyl ester 
• 1692-15-5 4-pyridylboronic acid 
• 710335-28-7 4-((S)-2-amino-4-tert-butoxycarbonyl-butyryl)piperazine-1-carboxylic acid ethyl ester 
• 120-43-4 4-ethoxycarbonylpiperazine 
• 3886-08-6 5-tert-butyl N-benzyloxycarbonyl-L-glutamate 
• 710335-29-8 ethyl 4-((2S)-2-([(benzyloxy)carbonyl]amino)-5-tert-butoxy-5-oxopentanoyl)piperazine-1-carboxylate 
• 325685-75-4 4-Chloro-6-hydroxymethyl-2-phenylpyrimidine 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 618-39-3 benzamidin 
• 1148122-15-9 6-chloro-2-phenylpyrimidine-4-carbonyl chloride 
• 339278-89-6 6-methoxymethyl-2-phenylpyrimidin-4-ol 
• 325685-59-4 4-chloro-6-methoxymethyl-2-phenylpyrimidine 
• 913952-59-7 6-chloro-2-phenylpyrimidine-4-carboxylic acid 

Downstream Products

• 913951-07-2 4-{(S)-4-carboxy-2-[(2-phenyl-6-pyridin-4-yl-pyrimidine-4-carbonyl)-amino]-butyryl}-piperazine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y12 antagonists for inhibition of platelet aggregation

2-Phenyl-pyrimidine-4-carboxamide analogs were identified as P2Y 12 antagonists. Optimization of the carbon-linked or nitrogen-linked substituent at the 6-position of the pyrimidine ring provided compounds with excellent ex vivo potency in the

Pyrimidine Derivatives and Their Use as P2Y12 Receptor Antagonists

The invention relates to 4-aminocarbonyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention and/or treatment of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular