91396-04-2

Usage

Uses

Used in Organic Synthesis:
1-(4-chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid methyl ester is utilized as an intermediate in the synthesis of pharmaceutical ingredients. Its unique structural features allow it to serve as a building block for creating biologically active molecules, contributing to the development of new drugs and therapeutic agents.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(4-chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid methyl ester is employed for its potential role in the development of novel drugs. Its chemical properties make it a valuable candidate for further research and testing, with the aim of identifying its full range of applications and uses in drug discovery.
Used as a Reference Standard in Analytical Chemistry and Drug Testing:
1-(4-chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid methyl ester is also used as a reference standard in the fields of analytical chemistry and drug testing. Its well-defined chemical structure and properties make it an ideal reference material for calibrating instruments and validating analytical methods, ensuring the accuracy and reliability of test results.

Upstream product

• 67-56-1 methanol 
• 39629-87-3 1-(4-chlorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid 
• 97-65-4 2-methylenesuccinic acid 
• 106-47-8 4-chloro-aniline 
• 617-52-7 Dimethyl itakonate 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 1342800-26-3 1-(4-chlorophenyl)-5-oxo-N'-(4-oxo-1,4-dihydronaphthalen-1-ylidene)pyrrolidine-3-carbohydrazide 
• 1342800-34-3 N'-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-(4-chlorophenyl)-5-oxopyrrolidine-3-carbohydrazide 
• 345249-49-2 1-(4-chlorophenyl)-5-oxopyrrolidin-3-carbohydrazide 
• 133748-52-4 methyl 3-<4-<1-(4-chlorophenyl)-2-oxo-pyrrolidin-4-yl>methyloxyphenyl>propionate 
• 133748-69-3 methyl 4-<2-<1-(4-chlorophenyl)-2-oxo-pyrrolidin-4-yl>ethyloxy>benzoate 
• 133747-66-7 Methyl 4-[1-(4-chlorophenyl)-2-pyrrolidon-4-yl]methoxybenzoate 
• 133748-55-7 Methyl 3-[1-(4-chlorophenyl)-2-pyrrolidon-4-yl]methoxybenzoate 
• 133748-54-6 methyl 2-<1-(4-chlorophenyl)-2-oxo-pyrrolidin-4-yl>methyloxybenzoate 
• 1027083-49-3 Methanesulfonic acid 2-[1-(4-chloro-phenyl)-5-oxo-pyrrolidin-3-yl]-ethyl ester 
• 133748-67-1 methyl 1-(4-chlorophenyl)-5-oxo-pyrrolidine-3-acetate 
• 133748-66-0 Methanesulfonic acid 1-(4-chloro-phenyl)-5-oxo-pyrrolidin-3-ylmethyl ester 
• 1027930-47-7 [1-(4-Chloro-phenyl)-5-oxo-pyrrolidin-3-yl]-acetic acid 

Relevant academic research and scientific papers

Efficient novel eutectic-mixture-mediated synthesis of benzoxazole-linked pyrrolidin-2-one heterocycles

In this study, new benzoxazole-linked pyrrolidinone heterocyclic compounds were synthesized by an eco-efficient strategy using substituted benzylamines and 2-aminophenol under ultrasonic irradiation in the presence of a newly designed metal-free deep eutectic solvent (DES). This DES was prepared by using a eutectic mixture of urea and a synthesized glycine-derived ionic liquid. X-ray diffraction and infrared spectroscopy were employed to investigate the structure of the ionic liquid and characterize the DES, respectively. This method exhibited key advantages of high productivity, a short reaction time, and simple processing. Moreover, this DES was easily separated from reaction mixtures and can be recycled for multiple reactions.

NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME

An amyloid fibril formation inhibitor comprising a compound represented by the following general formulae (I) to (III): wherein Q is -C(=O)-; X is -C(=O)-, -NH-C(=O)-; Y is -(CH2)m-; Z is -(CH2)n-; R1

Synthesis of 4-methyloxybenzoic acids and related compounds, and their inhibitory capacities toward fatty-acid and sterol biosynthesis

The synthesis of a series of 4-methyloxybenzoic acids and related compounds, and their evaluation for inhibitory capacity toward fatty-acid and sterol biosyntheses using rats' liver slices in vitro and rabbits

Phenylcarboxylic acid derivatives having hetero ring

Phenylcarboxylic acid derivatives having a hetero ring in the substituent of the formula: STR1 wherein R1 is halogen, alkyl, cycloalkyl, hydroxy, alkoxy, phenoxy which has a substituent selected from halogen and alkyl, carboxyl, alkylsulfonyloxy, phenylsulfonyloxy optionally substituted by halogen, alkylsulfonyloxyalkoxy, amino, alkanoylamino, benzoylamino, alkenyloxy, phenylalkoxyalkoxy, hydroxyalkoxy, phenylalkoxy having optionally 1 to 3 substituents selected from halogen, alkyl and alkoxy, halogenoalkyl, cycloalkyloxy optionally substituted by hydroxy, alkoxy substituted by cycloalkyl having optionally hydroxy substituent, imidazolylalkyl or imidazolylalkoxy; k is 0 or 1 to 3; or (R1)k is alkylenedioxy; A is alkylene or alkylenoxy; l is 0 or 1; B is methylene or carbonyl; m is 0 or 1; D is alkylene; E is alkylene or alkenylene; n is 0 or 1; and R2 is hydrogen or alkyl, or a salt thereof, which have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of arteriosclerosis, prophylactic and treating agent of obesity, antidiabetics.