91396-88-2 Usage
Uses
Used in Biomedical Research:
4-Pyridinecarboxylic acid, 2-phenylhydrazide is used as a research tool for studying the role of SCD1 in stem cell biology and its potential applications in regenerative medicine.
Used in Cancer Therapy:
4-Pyridinecarboxylic acid, 2-phenylhydrazide is used as an anticancer agent for selectively eliminating tumorigenic cells in various cell types, such as cardiomyocytes and chondrogenic cells. This selective elimination helps to improve the safety and efficacy of hPSC-based treatments and reduces the risk of tumor formation.
Used in Drug Development:
4-Pyridinecarboxylic acid, 2-phenylhydrazide serves as a lead compound in the development of new drugs targeting SCD1 and its role in stem cell biology, with potential applications in regenerative medicine and cancer therapy.
References
1) Ben-David?et al. (2013),?Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen; Cell Stem Cell.?12?167
2) Zhang?et al. (2014),?Inhibition of stearoyl-coA desaturase eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium; Cell Cycle?13?762
3) Cheng?et al. (2014),?Cartilage Repair Using Human Embryonic Stem Cell-Derived Chondroprogenitors; Stem Cells Transl. Med.?3?1287
Check Digit Verification of cas no
The CAS Registry Mumber 91396-88-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,3,9 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91396-88:
(7*9)+(6*1)+(5*3)+(4*9)+(3*6)+(2*8)+(1*8)=162
162 % 10 = 2
So 91396-88-2 is a valid CAS Registry Number.
