914076-05-4

Basic information

• Product Name: (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide
• Synonyms: (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide
• CAS NO: 914076-05-4
• Molecular Weight: 473.528
• Mol File: 914076-05-4.mol

Chemical Properties

• CAS DataBase Reference: (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide(914076-05-4)
• EPA Substance Registry System: (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide(914076-05-4)

Safety Data

• Hazardous Substances Data: 914076-05-4(Hazardous Substances Data)

Upstream product

• 914076-04-3 (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-7-carboxylic acid ((biphenyl-4-yl)methyl)amide 
• 622-33-3 N-benzyloxyamine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 250137-88-3 methyl (1S,5S,7R)-3-benzyl-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-exo-carboxylate 
• 712-76-5 N-(4-phenyl)benzylamine 
• 914076-03-2 (1S,5S,7R)-3-benzyl-3-aza-6,8-dioxabicyclo[3.2.1]octane-7-carboxylic acid ((biphenyl-4-yl)methyl)amide 

Relevant articles and documents

Synthesis of bicyclic molecular scaffolds (BTAa): An investigation towards new selective MMP-12 inhibitors

Starting from 3-aza-6,8-dioxa-bicyclo[3.2.1]octane scaffold (BTAa) a virtual library of molecules was generated and screened in silico against the crystal structure of the Human Macrophage Metalloelastase (MMP-12). The molecules obtaining high score were