914106-36-8Relevant articles and documents
1,2,4-oxadiazole-based bio-isosteres of benzamides: Synthesis, biological activity and toxicity to zebrafish embryo
Yang, Sen,Ren, Chao-Li,Ma, Tian-Yang,Zou, Wen-Qian,Dai, Li,Tian, Xiao-Yu,Liu, Xing-Hai,Tan, Cheng-Xia
, p. 1 - 14 (2021/03/03)
To discover new compounds with broad spectrum and high activity, we designed a series of novel benzamides containing 1,2,4-oxadiazole moiety by bioisosterism, and 28 benzamides derivatives with antifungal activity were synthesized. These compounds were ev
1,2,4-oxadiazole bipyridine substituted benzamide compound as well as preparation method and application thereof
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, (2020/09/08)
The invention belongs to the technical field of chemical synthesis and drug application, and particularly relates to a 1,2,4-oxadiazole bipyridine substituted benzamide compound as well as a preparation method and application thereof. The preparation meth
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
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Page/Page column 24-28; 41, (2010/11/24)
Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.