91419-60-2 Usage
Uses
Used in Pharmaceutical Industry:
4-(1H-Tetrazol-5-yl)-piperidine hydrochloride serves as a crucial building block in the synthesis of a variety of drugs. Its incorporation into drug molecules is driven by the compound's stability and the bioactive properties of the tetrazole group, which can enhance the therapeutic effects of the resulting medications.
Used in Cardiovascular Medications:
In the field of cardiovascular medicine, 4-(1H-Tetrazol-5-yl)-piperidine hydrochloride is utilized as a key intermediate for developing drugs aimed at treating disorders of the heart and blood vessels. Its structural attributes allow for the fine-tuning of drug interactions with biological targets, potentially leading to more effective treatments.
Used in Central Nervous System Therapies:
For central nervous system disorders, 4-(1H-Tetrazol-5-yl)-piperidine hydrochloride is employed in the creation of medications intended to address neurological conditions. 4-(1H-TETRAZOL-5-YL)-PIPERIDINE HYDROCHLORIDE's ability to engage with complex biological systems makes it a promising candidate for drugs that require precise action within the intricate environment of the CNS.
Overall, 4-(1H-Tetrazol-5-yl)-piperidine hydrochloride's role in the pharmaceutical industry is multifaceted, with applications spanning across different therapeutic areas, all underpinned by its chemical properties that facilitate its integration into effective drug molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 91419-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,4,1 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 91419-60:
(7*9)+(6*1)+(5*4)+(4*1)+(3*9)+(2*6)+(1*0)=132
132 % 10 = 2
So 91419-60-2 is a valid CAS Registry Number.
91419-60-2Relevant academic research and scientific papers
NOVEL IMIDAZOTRIAZINONE OR IMIDAZOPYRAZINONE DERIVATIVES, AND USE THEREOF
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Paragraph 332-334, (2016/04/26)
The present invention relates to novel a imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.
NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF
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Paragraph 275; 276; 277; 295; 296; 297; 375; 376; 377, (2016/01/25)
The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.
Tetrazole analogues of GABA-mimetic agents
Schlewer,Wermuth,Chambon
, p. 181 - 186 (2007/10/02)
Six tetrazole analogues of GABA-mimetic compounds were synthesized. In vitro only two compounds, analogues of GABA and isoguvacine, showed a weak affinity for GABA-A and GABA-B receptors. In vivo compounds were inactive in a psychopharmacological screening in mice. The results were interpreted in terms of intercharge distance, electronic delocalisation and ability of membrane crossing.
