91427-06-4

Basic information

• Product Name: Ethanone, 1-[4-(3-chloropropyl)phenyl]-
• CAS NO: 91427-06-4
• Molecular Formula: C11H13ClO
• Molecular Weight: 196.677
• Mol File: 91427-06-4.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(3-chloropropyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(3-chloropropyl)phenyl]-(91427-06-4)
• EPA Substance Registry System: Ethanone, 1-[4-(3-chloropropyl)phenyl]-(91427-06-4)

Safety Data

• Hazardous Substances Data: 91427-06-4(Hazardous Substances Data)

Usage

Uses

Used in Perfumery and Flavoring Industry:
Ethanone, 1-[4-(3-chloropropyl)phenyl]is used as a fragrance ingredient for its sweet, floral, and woody scent, adding depth and complexity to perfumes and enhancing the aroma of various food products.
Used in Pharmaceutical Synthesis:
This chemical compound is utilized as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Medicinal Chemistry:
Ethanone, 1-[4-(3-chloropropyl)phenyl]is studied for its potential antimicrobial and antifungal properties, making it a valuable compound in the research and development of new treatments for infectious diseases.
Used in Chemical Research:
As a versatile aromatic ketone, this compound is employed in various chemical research applications, exploring its reactivity, properties, and potential uses in the synthesis of other organic compounds.

Upstream product

• 109613-00-5 4-acetophenyl triflate 
• 104-52-9 phenylpropyl chloride 
• 75-36-5 acetyl chloride 
• 123655-43-6 C₁₁H₁₅ClO 
• 10537-63-0 1-(4-vinylphenyl)ethanone 

Downstream Products

• 1356411-41-0 1-{4-[3-(dibutylamino)propyl]phenyl}heptane-1,3-dione 
• 401925-43-7 isopropyl 2-butyl-3-{4-[3-(dibutylamino)propyl]benzoyl}-1-benzofuran-5-carboxylate 
• 1356411-42-1 1-{4-[3-(dibutylamino)propyl]phenyl}ethanone 

Relevant articles and documents

Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover

A benchtop stable, bifunctional reagent for the redox-neutral cyclopropanation of olefins has been developed. Triethylammonium bis(catecholato)iodomethylsilicate can be readily prepared on multigram scale. Using this reagent in combination with an organic photocatalyst and visible light, cyclopropanation of an array of olefins, including trifluoromethyl- and pinacolatoboryl-substituted alkenes, can be accomplished in a matter of hours. The reaction is highly tolerant of traditionally reactive functional groups (carboxylic acids, basic heterocycles, alkyl halides, etc.) and permits the chemoselective cyclopropanation of polyolefinated compounds. Mechanistic interrogation revealed that the reaction proceeds via a rapid anionic 3-exo-tet ring closure, a pathway consistent with experimental and computational data.

PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5

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One-pot synthesis of carbamoyl azides directly from primary alcohols and oxidation of secondary alcohols to ketones using iodobenzene dichloride in combination with sodium azide

An effective synthesis of carbamoyl azides directly from primary alcohols using iodobenzene dichloride in combination with sodium azide has been developed. Moreover, the same regent combination was also efficient for the oxidation of secondary alcohols to the corresponding ketones.

3-Azabicyclo[3.1.0]hexane derivatives useful in therapy

Compounds of formula I, where the substituents are as defined herein, and the pharmaceutically or veterinarily acceptable derivatives or prodrugs thereof, are pharmaceutically and veterinarily useful, in particular they bind to opiate receptors (e.g. mu,

B-alkyl suzuki-miyaura cross-coupling reactions with air-stable potassium alkyltrifluoroborates

The palladium-catalyzed cross-coupling reaction of substituted potassium alkyltrifluoroborates with aryl halides and aryl triflates proceeds readily with moderate to good yields. The potassium alkyltrifluoroborates 1, 2, and 3a-e were easily synthesized and obtained as air-stable crystalline solids that can be stored for long periods of time. All of the cross-couplings proceed under the same reaction conditions using PdCl2(dppf)·CH2cl2 as catalyst in THF-H2O in the presence of 3 equiv of Cs2CO3 as base.