91435-49-3Relevant academic research and scientific papers
Synthesis of C- and N-Substituted 1,5,2,6-Dithiadiazocanes –Electrophilic-Nucleophilic Thioamination (ENTA) Reagents
Bagd?iūnas, Gintautas,Javorskis, Tomas,Jurys, Arminas,Orentas, Edvinas
supporting information, p. 3329 - 3335 (2021/07/02)
A synthetic method is presented for S?N bond formation starting from cheap and affordable materials. We show that (un)substituted N-protected cyclic eight-membered C2-symmetric sulfenamides have been prepared in a few steps using this procedure. The synthetic utility of these ambipolar derivatives was demonstrated in a variety of synthetic transformations affording different S,N-heterocyles of pharmaceutical relevance in one or two steps from simple starting materials. (Figure presented.).
Synthesis of 2-Phenyl-, 3-Phenyl-, cis-2,3-Diphenyl-, and trans-2,3-Diphenyl-1,4-thiazanes and Derivatives (N-Methyl, N-Alkoxycarbonyl, S-Oxides, and S,S-Dioxides)
Ruano, J. L. Garcia,Martinez, M. C.,Rodriguez, J.H.,Olefirowicz, E. M.,Eliel, Ernest L.
, p. 4215 - 4224 (2007/10/02)
The syntheses of the title 1,4-thiazanes (thiamorpholines) by reduction of the 5-oxa-1,4-thiazanes resulting from the lactamization of the appropriate acyclic phenyl derivatives of 5-amino-3-thiapentanoic acid are reported.The oxidation reactions at sulfu
