914480-48-1 Usage
Description
(2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide dihydrochloride is a chiral compound with a unique molecular structure featuring a hexanamide backbone, two amino groups, and a substituted phenylethyl group. It is a pale beige solid, indicating its solid-state nature and potential for use in various applications.
Uses
Used in Pharmaceutical Industry:
(2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide dihydrochloride is used as an active pharmaceutical ingredient for the development of Lisdexamfetamine, a novel amphetamine product. It is utilized for its efficacy in providing up to 12 hours of activity in children and adults, with a side effect profile similar to other longer-acting amphetamine products.
Used in Drug Delivery Systems:
The chiral nature and solid-state properties of (2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide dihydrochloride make it a candidate for use in drug delivery systems. It can be employed to improve the bioavailability, stability, and targeted delivery of pharmaceutical agents, enhancing their therapeutic outcomes and reducing side effects.
Used in Chemical Research:
Due to its unique molecular structure and chiral properties, (2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide dihydrochloride can be used in chemical research for the development of new synthetic routes, chiral catalysts, and enantioselective reactions. This can lead to the discovery of new compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 914480-48-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,4,8 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 914480-48:
(8*9)+(7*1)+(6*4)+(5*4)+(4*8)+(3*0)+(2*4)+(1*8)=171
171 % 10 = 1
So 914480-48-1 is a valid CAS Registry Number.
914480-48-1Relevant articles and documents
ABUSE-RESISTANT AMPHETAMINE PRODRUGS
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Page/Page column 79-80, (2008/06/13)
The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.
