914672-66-5

Basic information

• Product Name: 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER
• Synonyms: 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER;1-TERT-BUTYOXYCARBONYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-2-YL)PYRRAZOLE;1-TERT-BUTYROLYCARBONYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOLONE-2-YL)PYRAZOLE;1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole;tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate
• CAS NO: 914672-66-5
• Molecular Formula: C₁₄H₂₃BN₂O₄
• Molecular Weight: 294.15
• Mol File: 914672-66-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 387.9±34.0 °C(Predicted)
• Appearance: /
• Density: 1.09±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: -1.34±0.12(Predicted)
• CAS DataBase Reference: 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER(914672-66-5)
• EPA Substance Registry System: 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER(914672-66-5)

Safety Data

• Hazardous Substances Data: 914672-66-5(Hazardous Substances Data)

Usage

General Description

1-Tert-butyloxycarbonylpyrazole-3-boronic acid pinacol ester, also known as Boc-pyrazole-Bpin pinacol ester, is a boronic acid derivative commonly used in organic synthesis. 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER is a versatile building block for the preparation of various biologically active molecules and pharmaceuticals. It features a Boc-protected pyrazole ring, making it suitable for use in Suzuki-Miyaura cross-coupling reactions to introduce the pyrazole moiety into different target molecules. Additionally, the pinacol ester functionality provides stability and ease of handling during synthetic processes. Overall, Boc-pyrazole-Bpin pinacol ester is an important reagent used in medicinal chemistry and chemical biology research for the development of new drugs and bioactive compounds.

Upstream product

• 121669-70-3 4-iodo-1H-pyrazole-1-carboxylic acid tert-butyl ester 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1312693-17-6 tert-Butyl 4-(6-((1R,2S)-2-(tert-butoxycarbonylamino)cyclohexylamino)-3-oxo-4-(m-tolylamino)-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-7-yl)-1H-pyrazole-1-carboxylate 

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