914922-81-9

Upstream product

• 914922-80-8 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-(benzyloxy)-4'-{(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-4-yl)-D-glucitol 
• 1027350-52-2 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-(benzyloxy)-4'-{(2R,3S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-4-yl)-D-glucitol 

Downstream Products

• 1027350-50-0 (1S)-1,5-anhydro-1-(4'-{(2R,3S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-1-phenylazetidin-2-yl}-3'-hydroxybiphenyl-4-yl)-D-glucitol 

Relevant academic research and scientific papers

PROCESSES FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES

The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula (I).

Process For Production Of 4-Biphenylyazetidin-2-Ones

The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula

PROCESSES FOR PRODUCTION OF DIPHENYLYLAZETIDIN-2-ONES AND RELATED COMPOUNDS

Processes for preparing a 4-biphenylylazetidinone of formula are described. The processes generally proceed by either cyclizing a biphenylyl-?aminoacyl compound or by arylating a 1-unsubstituted 4-biphenylylazetidinone with an R1-substituted phenyl arylating agent. Many of the processes may also be applied to the synthesis of 1,4-diphenylazetidinone deriviatives.