914922-80-8

Upstream product

• 591-50-4 iodobenzene 
• 1023283-13-7 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-(benzyloxy)-4'-{(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-azetidin-2-yl}biphenyl-4-yl)-D-glucitol 
• 914922-79-5 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-D-glucitol 
• 913369-88-7 (3R,4S)-4-[2-(benzyloxy)-4-bromophenyl]-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-phenylazetidin-2-one 
• 793673-93-5 (-)-6-(4-fluorophenyl)tetrahydro-2H-pyran-2-one 

Downstream Products

• 914922-81-9 (1S)-1,5-anhydro-1-(3'-(benzyloxy)-4'-{(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-4-yl)-D-glucitol 

Relevant academic research and scientific papers

Process For Production Of 4-Biphenylyazetidin-2-Ones

The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula

PROCESSES FOR PRODUCTION OF DIPHENYLYLAZETIDIN-2-ONES AND RELATED COMPOUNDS

Processes for preparing a 4-biphenylylazetidinone of formula are described. The processes generally proceed by either cyclizing a biphenylyl-?aminoacyl compound or by arylating a 1-unsubstituted 4-biphenylylazetidinone with an R1-substituted phenyl arylating agent. Many of the processes may also be applied to the synthesis of 1,4-diphenylazetidinone deriviatives.

PROCESSES FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES

The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula (I).