91493-71-9

Basic information

• Product Name: 2-nitrophenyl benzenesulfonate
• Synonyms: 2-Nitrophenyl benzenesulfonate
• CAS NO: 91493-71-9
• Molecular Formula: C₁₂H₉NO₅S
• Molecular Weight: 279.2686
• Mol File: 91493-71-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 456.4°C at 760 mmHg
• Flash Point: 229.8°C
• Density: 1.432g/cm³
• Vapor Pressure: 4.39E-08mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 2-nitrophenyl benzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitrophenyl benzenesulfonate(91493-71-9)
• EPA Substance Registry System: 2-nitrophenyl benzenesulfonate(91493-71-9)

Safety Data

• Hazardous Substances Data: 91493-71-9(Hazardous Substances Data)

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 88-75-5 2-hydroxynitrobenzene 

Downstream Products

• 69036-77-7 2-aminophenyl benzenesulfonate 
• 88-75-5 2-hydroxynitrobenzene 

Relevant articles and documents

Deprotection of durable benzenesulfonyl protection for phenols — efficient synthesis of polyphenols

A robust protection method for phenol was demonstrated by the use of durable benzenesulfonyl group, which survives various harsh reaction conditions using Grignard reagent, organolithium reagent, metal alkoxide, phosgene, mineral, and Lewis acids. A facile deprotection condition utilizing pulverized KOH (5 equiv) and t-BuOH (10 equiv) in hot toluene makes this protocol as a practical method, which can be applied to the multistep synthesis of biologically and medicinally important polyphenol compounds.