914950-77-9 Usage
Uses
Used in Pharmaceutical Industry:
1-(6-Bromo-2-pyridyl)ethylamine is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its role in the synthesis process is vital for creating complex molecular structures with potential medicinal properties.
Used in Organic Synthesis:
As a ligand in metal-catalyzed reactions, 1-(6-Bromo-2-pyridyl)ethylamine is used to facilitate organic synthesis processes. Its ability to coordinate with metal catalysts enhances the efficiency and selectivity of these reactions, making it an indispensable tool in the synthesis of complex organic compounds.
Used in Research and Development:
1-(6-Bromo-2-pyridyl)ethylamine is utilized as a building block in the research and development of new drugs and bioactive compounds. Its unique structural features and reactivity make it a promising candidate for the creation of novel therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 914950-77-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,9,5 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 914950-77:
(8*9)+(7*1)+(6*4)+(5*9)+(4*5)+(3*0)+(2*7)+(1*7)=189
189 % 10 = 9
So 914950-77-9 is a valid CAS Registry Number.
914950-77-9Relevant academic research and scientific papers
BICYCLIC COMPOUNDS
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Paragraph 00439, (2020/06/01)
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.
Novel tricyclic inhibitors of IKK2: Discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6- dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066)
Watterson, Scott H.,Langevine, Charles M.,Van Kirk, Katy,Kempson, James,Guo, Junquing,Spergel, Steven H.,Das, Jagabandhu,Moquin, Robert V.,Dyckman, Alaric J.,Nirschl, David,Gregor, Kurt,Pattoli, Mark A.,Yang, Xiaoxia,McIntyre, Kim W.,Yang, Guchen,Galella, Michael A.,Booth-Lute, Hollie,Chen, Laishun,Yang, Zheng,Wang-Iverson, David,McKinnon, Murray,Dodd, John H.,Barrish, Joel C.,Burke, James R.,Pitts, William J.
, p. 7006 - 7012 (2012/01/13)
The synthesis, structure-activity relationships (SAR), and biological results of pyridyl-substituted azaindole based tricyclic inhibitors of IKK2 are described. Compound 4m demonstrated potent in vitro potency, acceptable pharmacokinetic and physicochemical properties, and efficacy when dosed orally in a mouse model of inflammatory bowel disease.
