914955-64-9

Upstream product

• 4248-19-5 tert-butyl carbazate 
• 122-78-1 phenylacetaldehyde 
• 914955-62-7 [1-(4-methylbenzenesulfonyl)-2-phenylethyl]carbamic acid tert-butyl ester 
• 914955-63-8 [1-benzyl-5-(tert-butyldiphenylsilanyloxy)-2,4-dimethylpent-2-enyl]carbamic acid tert-butyl ester 

Downstream Products

• 914955-66-1 Boc-D-Phe-ψL[(E)-C(CH3)=CH]-Ala-Val-OMe 
• 914955-65-0 (S)-2-((E)-(2R,5S)-5-tert-Butoxycarbonylamino-2,4-dimethyl-6-phenyl-hex-3-enoylamino)-3-methyl-butyric acid methyl ester 
• 914955-67-2 Boc-D-Phe-ψ[(E)-C(CH3)=CH]-Ala-Val-Orn(Cbz)-Leu-OMe 
• 85613-64-5 (S)-3-(tert-butoxycarbonyl)amino-4-phenyl-2-butanone 

Relevant academic research and scientific papers

Trisubstituted (E)-alkene dipeptide isosteres as β-turn promoters in the gramicidin S cyclodecapeptide scaffold

(Chemical Equation Presented) A concise synthesis of a gramicidin S analogue with trisubstituted (E)-alkene dipeptide isostere (TEADI) replacements at both D-Phe-Pro positions was realized. Conformational analysis demonstrated that TEADIs can serve as typ