914955-67-2

Upstream product

• 914955-64-9 [benzyl-5-hydroxyl-2,4R-dimethylpent-2-enyl]carbamic acid tert-butyl ester 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 122-78-1 phenylacetaldehyde 
• 88489-27-4 Nα-tert-butoxyacrbonyl-Nδ-benzyloxycarbonyl-L-ornityl-L-leucine methyl ester 
• 2480-93-5 Boc-Orn(Z)-OH 
• 4248-19-5 tert-butyl carbazate 
• 914955-63-8 [1-benzyl-5-(tert-butyldiphenylsilanyloxy)-2,4-dimethylpent-2-enyl]carbamic acid tert-butyl ester 
• 914955-66-1 Boc-D-Phe-ψL[(E)-C(CH3)=CH]-Ala-Val-OMe 
• 914955-62-7 [1-(4-methylbenzenesulfonyl)-2-phenylethyl]carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Trisubstituted (E)-alkene dipeptide isosteres as β-turn promoters in the gramicidin S cyclodecapeptide scaffold

(Chemical Equation Presented) A concise synthesis of a gramicidin S analogue with trisubstituted (E)-alkene dipeptide isostere (TEADI) replacements at both D-Phe-Pro positions was realized. Conformational analysis demonstrated that TEADIs can serve as typ